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. This PhD project will address these critical gaps through an ambitious translational research programme combining human studies with cutting-edge laboratory science. The student will design and lead a
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physiological and blood-based markers linked to left atrial thrombogenicity in AF, supporting more personalised stroke prevention. Project plan Phase 1: Cohort discovery in PREFER-CMR (n ~2,000): Using the PREFER
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provide considerable training in chronobiology, signal transduction in plants, microbiology, and data analysis and interpretation. As part of the “MicroClock” programme funded through an ERC Synergy grant
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that drives this we plan to identify therapeutic targets that could prevent the progression of MGUS to myeloma. Research Methodology This PhD project will investigate changes in the innate immune system in MGUS