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research laboratory focused on understanding lymphoma biology through integrated mouse models, in vitro systems, and human biospecimen analyses. This position is responsible for supervising laboratory
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remain largely unknown. The aim of our project is to use animal models to identify the brain signature of CR, based on the heterogeneity of CR levels observed in clinical trials. To this end, our research
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uses an interdisciplinary approach that integrates quantitative microscopy, live-cell imaging, molecular and cellular biology, computational analysis, and cancer model systems to investigate how
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of molecular biology (PCR and qPCR) for genotyping mouse models, and maintain colony of transgenic and KO mice. Proficiency in techniques of immunohistochemistry and morphometric analysis of tissues harvested
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the treatment of leukemia, development of transgenic animal models of leukemia, harvesting and cryopreserving hematopoietic tissues from these animals. The position will also include the isolation, processing
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behavioral recovery assessments (e.g., mNSS, CatWalk, adhesive removal) with molecular endpoints. Experience with Prism for statistical modeling preferred. * Mentorship: Act as technical lead and advisor
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diseases and anti-cancer immune responses in both animal models and humans. This position will entail a variety of research procedures, including molecular biology (PCR, DNA sub cloning, sequencing, protein
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molecular modelling methods, including molecular mechanics, molecular dynamics and quantum mechanics. Practical experience with small-molecule binding affinity prediction, e.g. MM/PBSA and free
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to support our research program investigating mechanisms underlying transcription factor regulation of gene expression in cellular differentiation and reprogramming. We are interested in the molecular basis
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Qualifications At least 1 year of related laboratory experience Experience in mouse work and studies using mouse models Experience in related laboratory procedures and techniques (e.g. molecular biology, mammalian