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interested in genome dynamics in Paramecium. The IJM is located on the Paris Cité University campus in the Paris-Rive Gauche business district (13th arrondissement of Paris; accessible by all means
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lifetime microscopy and single-molecule localization microscopy, with the aim of enabling dynamic observation of living biological systems and nanostructures. This research lies at the interface of physics
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, while preserving ultimate precision in single-molecule localization and access to key photophysical parameters (fluorescence lifetime, brightness, molecular dynamics). This approach paves the way toward
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presence or absence of TSPANC8 proteins. ADAM10 dynamics, as measured by SMT, will help to understand this molecular landscape. This project is funded by an INCA French grant. References - Fernandez et al
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subcellular localization or actin dynamics, the candidate will investigate the impact of mitochondrial activity and the actin network on germ granule functional organization. - Drosophila genetics - Molecular
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, protein and lipid chromatography (FPLC, HPTLC), various spectrophotometers (UV-visible, CD, fluorimeters), and computers for molecular dynamics simulation. The IPMC institute includes various state
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performing atomistic simulations with Density Functional Theory and Molecular Dynamics. Data analysis and coarse graining in order to provide parametrisations for upper scale models (Kinetic Monte Carlo and
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, we observed size-specificity in the adaptation process at the phenotypic, genetic and mechanistic levels. However, we still do not understand the molecular pathways by which cell size shapes cellular
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in a rapidly developing field • Access to state-of-the-art equipment and radiation sources including synchrotron radiation facilities • A dynamic, diverse, and international research environment with
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interdisciplinary and international working environment, with state-of-the-art imaging and cell and molecular biology platforms, as well as access to the IPGG's microfabrication and microfluidics platform. Where