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. To this end, we develop mathematical and computational approaches to estimate mutation rates, tumor growth dynamics and selection. Analysis of the mutational processes acting in cancer genomes allows us to
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these questions, we develop mathematical and computational approaches to estimate mutation probabilities and selection. Tumor mutations are caused by diverse mutational processes, which can be identified through
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are influenced by the influx of mutations and by selective pressures, as inferred from mutation data. To address these questions, we develop mathematical and computational approaches to estimate mutation
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