Research Assistant 3

Case Western Reserve University, United States

Updated: 1 day ago
Location: Campus, ILLINOIS
Job Type: FullTime

Case Western Reserve University is committed to providing a transparent estimate of the salary range available for this position at the time of its posting. The salary range is between $46,036 and $58,234, depending on qualifications, experience, department budgets, and industry data. 

Employees receive more than just a paycheck. University employees enjoy a comprehensive benefits package that includes excellent healthcare, retirement plans, tuition assistance, paid time off, and a winter recess.

POSITION OBJECTIVE

Working under limited supervision, coordinate research work in medical and related technical areas. The Research Assistant 3 will also perform data analysis on public and lab datasets using multi-omics approaches. The research assistant will also perform wet lab work in field of neurodegenerative diseases, involving use of lab/research skills involving mouse breeding, behavioral testing of mice, and surgical procedures in mice. Other work includes Western blotting and cell cultures. This position will work with animals. 

 

ESSENTIAL FUNCTIONS 

  • Coordinate laboratory/ research activities. Plan and carry out projects in accordance with general plans. Perform statistical analysis on public/lab datasets for scRNA-seq and proteomics results, as well as genome-wide association study (GWAS) analysis to identify genetic variants in neurodegenerative diseases. (30%)
  • Work closely with the principal investigator. Assist the principal investigator for funding application. (10%)  
  • Carry out complex research assignments of a non-routine nature. Perform research work in mouse models of neurodegenerative disease by breeding mice, tattooing or ear tagging mice, genotyping mouse tails by PCR and Real-time PCR, maintaining mouse databases, surgery (pre-, intra-, and post-operative procedures), and behavioral testing. (25%)  
  • Devise new protocols and techniques for research projects involving a high degree of skill and training. Learn new techniques such as RNA in situ hybridization and further develop existing techniques used in the laboratory. (10%)  
  • Evaluate adequacy of techniques; study and test new procedures and analyze data. Perform research work in the field of neurodegenerative diseases using cellular and molecular biology techniques, such as mammalian cell cultures, Western blotting, tissue and cell stating, and quantification and presentation of test results. (10%)

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    NONESSENTIAL FUNCTIONS 

  • May supervise students and technicians. Supervise undergraduates. (5%)
  • May co-author research projects. Assist in manuscript writing for paper publications. (5%)
  • May monitor the laboratory budget. Monitor the budget and report to principal investigator. (5%)
  • Perform other duties as assigned. (<1%)

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    CONTACTS 

    Department: Daily contact with supervisor to discuss research and maintain workflow.

    University: Occasional contact with other departments to share information.

    External: Limited or no contact with vendors to exchange information.

    Students: Contact with student employees to exchange information.

     

    SUPERVISORY RESPONSIBILITY 

    Supervise students.

     

    QUALIFICATIONS 

    Experience: 3 to 5 years of related experience required.

    Education: Bachelor of Science degree required.

     

    REQUIRED SKILLS 

  • Has knowledge of commonly-used concepts, practices, and procedures within a particular field. This position should have knowledge and strong skills in data analysis and statistics. Python and R skills are required.
  • Relies on instructions and pre-established guidelines to perform the functions of the job. 
  • Ability to operate laboratory equipment. This position will use Amersham ImageQuant 800 imager, LEICA CM1860 Cryostat, and Eppenforf Centrifuge 5415R. 
  • Demonstrated history of successful support, education, and advocacy for all students, aligned with the values, mission, and messaging of the university, while adhering to the staff policy on conflict of commitment and interest.
  • Ability to meet consistent attendance.
  • Ability to interact with colleagues, supervisors and customers face to face.
  • Must demonstrate compliance with university animal research and care (ARC) policies and procedures and compliance to regulations of the Animal Welfare Act, Public Health Service Policy, AAALAC guidelines and other applicable regulatory guidelines. 
  • Must be able and willing to learn new techniques, procedures, processes, and computer gear to protect the health of the animals. 
  • Previous experience working with animals preferred.

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    WORKING CONDITIONS

    Identify the working conditions and physical demands, which relate to the essential functions of the position, such as working indoors/ outdoors, working with exposures to hazards, etc. Include special considerations for the position, such as occasional travel or necessary overtime. 

    General laboratory environment. May have exposure to hazards. This position will be in contact with live mice and mouse tissues. Biosafety and IACUC training in addition to basic lab standard training will be required.

    Case Western Reserve University's animal facilities are accredited by the Associate for the Assessment and Accreditation of Laboratory Animal Care (AAALAC) and is managed according to the ¿Guide for the Care and Use of Laboratory Animals¿ appropriate Federal Animal Welfare Regulations, and the Public Health Service ¿Policy on the Humane Care and Use of Laboratory Animals.¿ This position and all animal research personnel are subject to internal compliance to the School of Medicine's Animal Resource Center Standard Operating Procedures and to compliance regulations of the Animal Welfare Act, Public Health Service Policy, AAALAC guidelines, the State of Ohio Veterinary Practice Act, Federal Drug Enforcement Administration regulatory guidelines, US Food and Drug Administration Center for Veterinary Medicine regulations and other applicable regulatory guidelines. 

     

    Case Western Reserve University is an equal opportunity employer.  All applicants are protected under federal and state laws and university policy from discrimination based on race, color, religion, sex, sexual orientation, gender identity or expression, national or ethnic origin, protected veteran status, disability, age and genetic information.

    Case Western Reserve University complies with the Americans with Disabilities Act regarding reasonable accommodations for applicants with disabilities. Applicants requiring a reasonable accommodation for any part of the application and hiring process should contact the CWRU Office of  Equity at 216-368-3066 to request a reasonable accommodation. Determinations as to granting reasonable accommodations for any applicants will be made on a case-by-case basis.

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