Research Associate in DNA Repair Biochemistry

This postdoctoral position will support a research programme in Professor Nigel Savery’s laboratory, focusing on DNA repair—particularly the mechanisms of nucleotide excision repair and the role of UvrD in transcription-coupled repair. The post is funded by the University of Bristol, and the role holder will have some teaching responsibilities as outlined in the job description. The post is closely linked to an EPSRC-supported doctoral training network, through which two PhD students are pursuing related projects, and forms part of an active collaboration with the Dillingham laboratory at the University of Bristol. The successful candidate will contribute to the scientific development of these projects while also leading independent and collaborative research within the lab.

• Design and conduct biochemical experiments investigating DNA–protein interactions relevant to nucleotide excision repair and transcription-coupled repair.
• Develop and optimise assays (e.g., DNA repair assays, EMSA, fluorescence anisotropy).
• Collaborate closely with PhD students and support their training and development.
• Analyse and interpret experimental results; contribute to publications and dissemination.
• Assist with lab organisation, compliance, and reporting.
• Supervise undergraduate research projects and contribute to teaching activities where appropriate.

• You hold a PhD (or working towards one) in biochemistry, molecular biology, or a related discipline.
• You have extensive experience in protein expression and purification, including Fe–S cluster proteins.
• You are skilled in quantitative DNA–protein interaction assays (EMSA, fluorescence-based approaches).
• You have a strong background in DNA repair research and can design and troubleshoot complex biochemical experiments.
• You communicate effectively and work well in a collaborative research environment.

For informal enquiries please Professor Nigel Savery, Head of School (n.j.savery@bristol.ac.uk or +44 (0)117 455 5087)

Contract type: Open ended with fixed funding to 31/7/27

Work pattern: Full-time

Grade: I

Salary:  £39,906 - £44,746 per annum

School/Unit: School of Biochemistry & Cellular and Molecular Medicine

This advert will close at23:59 UK timeon Tuesday 16th December 2025

We recently launched our strategy  to 2030 tying together our mission, vision and values.

The University of Bristol aims to be a place where everyone feels able to be themselves and do their best in an inclusive working environment where all colleagues can thrive and reach their full potential. We want to attract, develop, and retain individuals with different experiences, backgrounds and perspectives – particularly people of colour, LGBT+ and disabled people - because diversity of people and ideas remains integral to our excellence as a global civic institution.

Available documents

This postdoctoral position will support a research programme in Professor Nigel Savery’s laboratory, focusing on DNA repair—particularly the mechanisms of nucleotide excision repair and the role of UvrD in transcription-coupled repair. The post is funded by the University of Bristol, and the role holder will have some teaching responsibilities as outlined in the job description. The post is closely linked to an EPSRC-supported doctoral training network, through which two PhD students are pursuing related projects, and forms part of an active collaboration with the Dillingham laboratory at the University of Bristol. The successful candidate will contribute to the scientific development of these projects while also leading independent and collaborative research within the lab.

• Design and conduct biochemical experiments investigating DNA–protein interactions relevant to nucleotide excision repair and transcription-coupled repair.
• Develop and optimise assays (e.g., DNA repair assays, EMSA, fluorescence anisotropy).
• Collaborate closely with PhD students and support their training and development.
• Analyse and interpret experimental results; contribute to publications and dissemination.
• Assist with lab organisation, compliance, and reporting.
• Supervise undergraduate research projects and contribute to teaching activities where appropriate.

• You hold a PhD (or working towards one) in biochemistry, molecular biology, or a related discipline.
• You have extensive experience in protein expression and purification, including Fe–S cluster proteins.
• You are skilled in quantitative DNA–protein interaction assays (EMSA, fluorescence-based approaches).
• You have a strong background in DNA repair research and can design and troubleshoot complex biochemical experiments.
• You communicate effectively and work well in a collaborative research environment.

For informal enquiries please Professor Nigel Savery, Head of School (n.j.savery@bristol.ac.uk or +44 (0)117 455 5087)

Contract type: Open ended with fixed funding to 31/7/27

Work pattern: Full-time

Grade: I

Salary:  £39,906 - £44,746 per annum

School/Unit: School of Biochemistry & Cellular and Molecular Medicine

This advert will close at23:59 UK timeon Tuesday 16th December 2025

We recently launched our strategy  to 2030 tying together our mission, vision and values.

The University of Bristol aims to be a place where everyone feels able to be themselves and do their best in an inclusive working environment where all colleagues can thrive and reach their full potential. We want to attract, develop, and retain individuals with different experiences, backgrounds and perspectives – particularly people of colour, LGBT+ and disabled people - because diversity of people and ideas remains integral to our excellence as a global civic institution.

Available documents