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bioinformatics. The role will be responsible for developing and characterising human dorsal root ganglia cultures to benchmark the newly developed iPSC derived organoid model systems. This will include processing
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Neural Injury Group and the Neuromusculoskeletal Health and Science Lab with responsibility for contributing to a multi-lab MRC-funded research project aiming to develop advance humanised pain models
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About the Role Join the innovative research team within the Department of Oncology at the University of Oxford as a Postdoctoral Researcher in Bioinformatics and Human Tissue Modelling
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bioinformatics. The role will be responsible for developing and characterising human dorsal root ganglia cultures to benchmark the newly developed iPSC derived organoid model systems. This will include processing
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microscopy and in vivo modelling of cancer. This will be a collaborative project jointly supervised by Stephen Tait and Ed Roberts. You will join a young, dynamic interdisciplinary research team, based withing
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of mechanisms using advanced cell culture and animal models of stroke. Projects Aims: Broad aims include determining the presence of genetic variants in the human genome that are associated with stroke in
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leverage patient-derived material such as post-mortem tissue and cell models, including cellular reprogramming coupled with CRISPR gene editing. We use state-of-the-art sequencing methods e.g. Oxford
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tubes, or tissues, that aid in nerve repair, with the aim of improving and assisting the outcome of surgical nerve repair. The materials and devices are tested in vitro using a variety of models for
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, Caenorhabditis elegans, Mus musculus, and Homo sapiens, comparing short- and long-lived species. We will assess mRNA and protein expression across tissues and developmental stages, quantifying correlations between