Postdoctoral Researcher (Embryogenesis, Nuclear dynamics, Mechanobiology)

Organisation/Company

Research Organization of Information and Systems, National Institute of Genetics

Department

Laboratory of Quantitative Mechanobiology

Research Field

Biological sciences
Ethics in health sciences
Pharmacological sciences
Medical sciences
Neurosciences
Chemistry
Agricultural sciences
Technology
Anthropology
Environmental science

Researcher Profile

Recognised Researcher (R2)

Application Deadline

31 Mar 2026 - 23:59 (UTC)

Country

Japan

Type of Contract

Permanent

Job Status

Not Applicable

Hours Per Week

See description

Is the job funded through the EU Research Framework Programme?

Not funded by a EU programme

Is the Job related to staff position within a Research Infrastructure?

No

[Background of the recruitment and description of the project]
* Background of the recruitment and description of the project
The Shimamoto Lab at the National Institute of Genetics (NIG), Japan, conducts interdisciplinary research on early embryogenesis by integrating biophysics and developmental biology. We have recently discovered that mouse embryonic nuclei undergo profound structural and mechanical changes during a critical developmental window associated with the transition from the maternal to the zygotic program. Further, these nuclear changes are promoted by nuclear autophagy, and that nuclear softening and plasticization are essential for facilitating transcriptional bursts of embryonic genes required for normal development.
This position seeks a postdoctoral researcher who will proactively pursue experimental research building on these findings. Key research areas include: (i) elucidating the physical and structural properties of the nuclear lamina and the regulatory pathways governing nuclear autophagy in embryos; (ii) analyzing transcriptional activity and genome dynamics within the nucleus; and (iii) developing techniques for the artificial manipulation of nuclear structure and mechanics.
This project is partially supported by the JST CREST program, “Development of Super-Biological Tissues through Chemical Catalysis-driven Cell Fate Engineering,” and is expected to expand into multifaceted research through collaborations with experts in chemical biology, cancer and developmental biology.
https://shimamotolab.weebly.com

[Work content and job description]
Comprehensive scientific research activities related to the project described above, including experiments, data analysis, conference presentations, and manuscript preparation.

* Assigned department
Existing departments

[Work location]
* Address
411-8540 Shizuoka Yata 1111, Mishima

[Number of hired]
Number of hired:1 person(s)

Website

https://jrecin.jst.go.jp/seek/SeekJorDetail?fn=0&ln=1&id=D126010456&ln_jor=1

[Compensation]
Annual salary:3 million yen - 4 million yen
Wages description:Salaries are determined in accordance with the institute's guidline.
Working hours:08:30-17:15
Break time:12:00-13:00
Holidays :Weekends, national holidays, summer vacation, year-end and New Year holidays, and annual paid leave available (conditions apply)
Overtime and other explanations:Discretionary labor system is applied (Deemed working hours: 38 hours and 45 minutes/week).
Employment type:Others
Employment type description:Annual contract (fiscal year-basis)
Contract period:Nontenured
Contract period description:Contracts may be renewed annually based on work performance, with the current term extending through March 31, 2031, subject to annual evaluation.
From April 1, 2031 onward, further renewal may be possible for up to a maximum of 10 years from the initial date of employment, based on work performance, laboratory budget, and other relevant factors.
Probationary period:Probationary period absent

[Various systems]
Transportation expenses:available (conditions apply)

[Insurance]
Employees' Health Insurance:available
Employees' Pension Insurance:available
Worker's accident insurance:available
Employment insurance:available

[Measures for preventing passive smoking at the workplace]

[Supplementary explanation of compensation]

Number of offers available

1

Company/Institute

Research Organization of Information and Systems, National Institute of Genetics

Country

Japan

City

Shizuoka

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