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biology in atherosclerosis. The project will combine patient-derived endothelial colony-forming cells with advanced coronary artery imaging from patients at Barts Health NHS Trust to identify individuals
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derived fragments from fresh human tissues to test the effect of mutations · Prepare human samples for spatial transcriptomics and high-dimensional imaging experiments · Run CRISPR-based perturbation assays
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mentoring junior researchers and students. Essential experience includes tissue sample harvesting and preparation, in situ gene and/or protein detection and quantification, advanced microscopy and imaging
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Schwann cells, myelination assays, or co-culture systems, and familiarity with advanced imaging or quantitative image analysis will be desirable for the role. About the School/Department/Institute/Project
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parasite mutants, antibodies, spatial proteomics, real-time and super-resolution imaging, we will reveal essential protein domains and characteristics, will identify interacting protein partners and will
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, particularly women from ethnic minority groups. Results will be used to develop and test a prototype training module. Based at our Charterhouse Square/Whitechapel campuses, this three-year project will involve
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. Hand on experience with life cell imaging FRET/FLIM is highly desirable. About the School/Department/Institute/Project The Barts Cancer Institute (BCI) is a Cancer Research UK Centre of Excellence whose