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Max Planck Institute of Molecular Cell Biology and Genetics, Dresden | Dresden, Sachsen | Germany | 2 months ago
-protein assemblies performing quantitative single-molecule or imaging experiments developing novel biophysical or biochemical assays validating emergent principles in mammalian cells or disease models
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: Mathematical modelling will be used to investigate the processes and consequences of disease progression from liver fibrosis to cirrhosis to hepatocellular carcinoma (primary liver cancer), to select specific
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leftward flow in the left–right organizer (LRO), but the identity and mechanism of the flow-transported symmetry-breaking cue has long remained elusive. Defects in this process are a major cause of
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quantitative live-cell imaging to probe and model these processes. By combining stem cell biology with cutting-edge microscopy and physical concepts, we aim to establish a predictive framework for tissue self
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-on experience in analytical techniques (e.g., biochemical assays, advanced Imaging technologies, Immunological and toxicological assays) Experience with genetically encoded delivery vehicles Your Personal
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, SimBA) Experience in animal experimentation (FELASA or equivalent is a requirement) Expertise in molecular biological and advanced imaging (confocal and fluorescence) techniques and analysis programs
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organizational levels of the brain – from molecular and cellular processes to complex neuronal networks and behavior. The research group “Behavioral Neuroscience” focuses on decoding the exact mechanisms behind
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to the translation of the four core optogenetic approaches to restore i) hearing and ii) vision and explore the potential of optogenetics for iii) gastric pacemaking and iv) brain-computer interfaces. These four teams
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transcriptomics programme to gain deeper insights into how different types of brain tumours grow and how brain tumour and brain resident cells interact in this process. You will contribute to these research efforts
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and brain resident cells interact in this process. You will contribute to these research efforts by analysing spatial transcriptomics data from hundreds of brain tumours to establish the molecular