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Assistant/Associate/Full Professor of Surgery – Genome Editing Delivery Expert UCSF Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research (Broad Center) Department of Surgery
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a supportive and hardworking team of scientists based in the School of Biosciences and the Bateson Centre. The student will use cutting-edge techniques such as CRISPR/Cas9 gene editing, light sheet
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consequences of its mutation in cancers. Summary aim: This project will investigate the nuclear function of TPL-2 kinase. Techniques: Cell culture, protein-protein interaction studies, CRISPR/Cas9 gene editing
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). We use a combination of developmental biology models including Xenopus (frog), mouse, and pluripotent stem cells, gene editing, and microscopy techniques to investigate the disease genetics and
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for collection, verification, statistical analysis, and management of data. Experiments would include cell culture, molecular biology (including gene editing), antibody production and engineering, flow cytometry
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PCR, ELISA; microscopy; flow cytometry; immunostaining; and experience with animals (i.e., mouse handling, organ collection). Experience in genetic modification techniques, including gene editing (e.g
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in Chlamydomonas using CRISPR-Cas9 gene editing approaches (ii) Spectroscopic characterisation of growth and photosynthesis in the mutant cells (iii) Biochemical purification of tagged complexes. (iv
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is focused on understanding the mechanisms of cardiovascular development, disease, and regeneration. For more details, please visit our lab website: https://www.nationwidechildrens.org/research/areas
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, molecular biology and gene therapy approaches. References Cardiovascular Research, Volume 116, Issue 8, 1 July 2020, Pages 1410–1423, https://doi.org/10.1093/cvr/cvaa034 Contact email: Christopher.Loughrey
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classification policy and practice o Searching and editing in the Alma Cataloging Module and OCLC Connexion client Native or proficient speaker of one of the languages listed in the Specialty Factor