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be removed before the deadline. Hypothesis: We hypothesize that a tailored library of wavelength-tuned, biocompatible carbon dots (C-dots) can serve as multifunctional fluorescent probes
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in the Department of Bioengineering at Helmholtz Munich . Our group focuses on the development and application of genetically encoded agents, primarily for photoacoustic and fluorescence imaging.We use
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infection in standardised model systems such as A549 cells. We have successfully produced a toolbox of fluorescently labelled influenza viruses, including spherical strains (A/WSN/33) and filamentous strains
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. In this project, you will use a combination of advanced fluorescence microscopy and virological methods to study how viruses overcome the glycocalyx barrier to reach the cell surface. The focus is on
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on optical tweezers, atomic force microscopy and advanced fluorescence microscopy to characterize the biophysical properties of the endothelial glycocalyx with suitable cellular and molecular models
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of bacteria are advantageous, as is experience with fluorescence microscopy and bioinformatics. We are looking for highly motivated and team-oriented candidates with a passion for science and excellent written
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vivo, using fusogenic liposomes to improve mechanical membrane properties Methods, such as micropipette aspiration, fluorescence spectroscopy and microscopy, MALDI-TOF, and basic cell culture Summarizing
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fluorescence methods, e.g., spectroscopy and microscopy Computational simulation of the molecular interactions within the liposomal membrane in cooperation with expert teams Summarizing your results in
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techniques. Biological tools: cell culture; working with breast cancer cell lines; immunofluorescent labelling, flow cytometry; fluorescent time-lapse and confocal microscopy; bioassays Spectroscopy: cutting
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cells Analyze RNA sequencing-based transcriptomic data sets Perform immune-staining with flow cytometry analysis, advanced microscopy techniques (light-sheet microscopy, confocal fluorescence microscopy