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fluorescence and soft-X ray imaging Generate a model of mammalian cell infection with influenza virus and characterise the time-course of ultrastructural changes. Assign structural variability profiles given a
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be removed before the deadline. Hypothesis: We hypothesize that a tailored library of wavelength-tuned, biocompatible carbon dots (C-dots) can serve as multifunctional fluorescent probes
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, spectroscopy, and imaging instruments forward to complement our molecular tools. One of our main topics are so-called photoswitching proteins whose photophysical properties (e.g. on/off fluorescence emission
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in mammalian cell culture. Have experience in cell imaging/microscopy (wide-field or confocal fluorescence microscopy) and/or molecular biology techniques (electrophoresis, Western blotting, IHC
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-time imaging. This PhD project aims to address these barriers by developing AI-driven methods for fluorescence fluctuation super-resolution microscopy (FF-SRM), with a particular focus on the emerging
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, high-content imaging and high-throughput screening methods combined with drug design and development. Compounds will be tested in standard cell lines as well as patient-derived cells and three
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of genetically encoded agents, primarily for photoacoustic and fluorescence imaging.Using technologies like photoacoustic imaging, we seek to visualize small populations of labeled cells (e.g. immune cells) deep
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microscopy, microscopy, light sheet fluorescence microscopy) and flow cytometry is an advantage Confident handling of Microsoft Office (Excel, PowerPoint, etc.) and image processing software (e.g. ImageJ
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authority of the MESR. Super-resolution imaging in optical microscopy now achieves nanometric resolution without requiring electron microscopy. However, it currently remains limited to the use of fluorescent
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injury following myocardial infarction. The study employs various imaging modalities, including confocal laser scanning microscopy and light sheet fluorescence microscopy, alongside flow cytometric and