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. This Postdoctoral Fellow position is in the chemistry research group led by Dr. Ajith Karunarathne in the Department of Chemistry (www.ajithlab.org). This work involves protein engineering and developing the cryo-EM
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understand the correlation between dengue vaccine protection and antibody enhancement. Unwanted/unsafe epitopes will be removed via viral engineering. Research skills in structural, engineering, and evolution
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of the underlying interactions. The approach uses a combination of conventional (rapid kinetics, protein engineering, X-ray crystallography) and innovative (smFRET, cryo-EM) biophysical techniques. Current projects
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Biochemical Techniques: Mammalian cell culture, cloning, lentiviral generation, cell line generation, animal handling and husbandry. Experience with CRISPR technology or unbiased prime editing screens would be