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edge functional genomics and biochemical techniques to understand how membrane proteins get made in human cells. This position would involve working with a range of techniques including CRISPR screening
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commitment) in studies in developing and/or applying cutting-edge CRISPR synthetic biology and functional genomics approaches to topics with therapeutic relevance. Some questions/challenges we are interested
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for targeted therapeutics, genes that could act as an “Achilles heel” for cancer cells while minimizing off-target effects on healthy tissues. To approach this, we use targeted and large-scale CRISPR/Cas9-based
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tumor tissue and apply cutting-edge CRISPR and single-cell techniques to interrogate gene function in primary cells. We are recruiting an SRA to assist with projects across the lab and perform lab
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of Ect2 in PDAC patient tumours The project will use a combination of cell and molecular biology approaches (including CRISPR gene editing, western blotting, flow cytometry), advanced microscopy (live cell
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website for more information about our research interests: https://krupina.lab.uiowa.edu This position is designed for individuals who: • Seek training, experience, and mentoring in a research setting
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-leading research in several fields. Notably, the groundbreaking discovery of the CRISPR-Cas9 gene-editing tool, which was awarded the Nobel Prize in Chemistry, was made here. At Umeå University, everything
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computational biology. The general responsibilities of this position are as follows: Independent analysis of single cell and bulk genomics data including from CRISPR screens, kidney organoid models, and primary
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a supportive and hardworking team of scientists based in the School of Biosciences and the Bateson Centre. The student will use cutting-edge techniques such as CRISPR/Cas9 gene editing, light sheet
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scientifically sound conclusions. 5. Ability to work well as part of a team. Enjoys working with people. Preferred Skills and Abilities 1. Experience with genome editing/ transgenesis (e.g. CRISPR/Cas9-based