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genes in in early embryonic development. Involves isolation and analysis of mouse embryos and in parallel CRISPR-based genetic engineering of embryonic stem cells and the analysis of this model system
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peuplier, une espèce modèle à croissance rapide et d'une grande importance économique. La thèse utilisera la technologie CRISPR-Cas pour éditer le génome des peupliers et combiner rapidement des allèles
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, genomics and single-cell molecular analyses, and computational modelling to uncover the principles guiding human embryogenesis. For more information about the laboratory please visit https
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the lab website: https://thegigerlab.org/ Scientific Research (80%) Perform nerve histological analyses using immunofluorescence, RNAscope in situ hybridization, and ultrastructural approaches Conduct cell
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endothelial cells, ChIP, immunohistochemistry, cloning, and/or advanced molecular biology techniques (including cloning, lentiviral shRNAi and/or CRISPR/Cas9 in mammalian cells), is mandatory. Experience and
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: https://doschem.univie.ac.at/ The employment duration is 3 years. Initially limited to 1.5 years, the employment relationship is automatically extended to 3 years if the employer does not terminate it
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to study cancer evolution, including developing CRISPR-based molecular recording tools to track tumor evolution history, modeling tumor progression using genetically engineered mouse models, applying single
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the manufacturing challenges associated with producing rAAV and brings together experts from two leading Irish institutions, NIBRT and UCD, and APC-VLE Ltd. (https://approcess.com/services/cell-and-gene-therapies
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. Research project activities may include: ⢠Mosquito breeding and behavioral experiments ⢠Generation of transgenic strains using CRISPR/Cas9 ⢠Molecular biology studies including DNA/RNA extraction, PCR
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insecticide resistance mechanisms, with focus on CRISPR/Cas9 Experience in confocal microscopy Experience in RNAi Research technician position #2 Required qualifications: BSc in Biology/Molecular Biology