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-leukemia (e.g. Beneyto-Calabuig et al., Cell Stem Cell 2023 ). A specific focus is the use of genetic screens (E.g. CRISPR screens, Perturb-Seq, MPRA) in primary hematopoietic stem cell models
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proteins identified from this screen will be validated using siRNA-mediated knockdown and CRISPR knockout in bacterial adherence assays to determine which specific cell surface proteins mediate interactions
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at the finest scale to create impact on a global scale. For more information on the Weiss laboratory: https://www.lsi.umich.edu/science/our-labs/weiss-lab Job Summary Please note: This position is term-limited
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lab, gene editing, gene augmentation, CRISPR technologies, immunotherapy, and CAR-T cell therapy, designed to provide advanced scientific training while preparing students for highly valued professional
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, Chikungunya, and yellow fever. The lab has developed CRISPR/Cas9 genome-editing in the Aedes aegypti mosquito with the goal of understanding how behaviors emerge from the integration of sensory input with
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to work with animal models of disease. Familiarity with RNA biology, epigenetics, CRISPR-based approaches, or next-generation sequencing workflows. Experience contributing to peer-reviewed publications
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with primary synovial cells obtained from joints from arthritis patients (e.g., CRISPR knock-outs and phosphoproteomics signaling), in vivo arthritis models in newly generated transgenic mice (e.g
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sophisticated molecular biology tools creating receptor mutants using CRISPR and knock-downs with siRNA. We're seeking a highly motivated and curious scientist with a strong foundation in Pharmacology
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, including the production of gene-edited (knockout) poultry using CRISPR/Cas9 technology and the development of poultry lines resistant to bacterial and viral infections. Duties and Responsibilities: (70
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Center. This position will organize and maintain multiple end user requests across Neuroscience community, including CRISPR screens, high throughput screens of neuronally differentiated iPSC cells