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Cytogenetics and Molecular Laboratory is staffed by approximately 18 technologists, two bioinformaticians, one post-doc and three faculty directors. The laboratory performs chromosome analysis, fluorescence in
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-fate determination, genome editing, the role of chromosome structure and chromatin modification in gene regulation, and the molecular evolution of chromosome-wide mechanisms of gene control in
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group has used their expertise in computer simulations on small model chromosomes to demonstrate that polymer-assisted condensates are capable of maintaining the epigenetic state through 40 generations
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include e.g. data quality controls, mapping of DNA data to reference genomes, investigation of deamination patterns, analysis of sex chromosomes, analysis of mitochondrial and Y-chromosome haplogroups
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altération de l'équilibre des populations de bactériophages (ou phages) tempérés et virulents. Les phages tempérés intègrent leur information génétique dans le chromosome de la bactérie-cible sous forme de
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the molecular mechanisms that initiate chromosome shattering, with a particular focus on cytoplasmic DNA nucleases that gain access to chromosomes after nuclear envelope rupture. Our work aims to define how “all
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chromosomal instability and telomere spectrum disorders, including Fanconi Anaemia and Bloom Syndrome. You will be embedded within the Genome Stability Laboratory and the PRECISE Proton Research Group, gaining
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of DNA in each of our cells, which needs to be divided once every cell cycle. To ensure faithful division of our genome, cells have enzymes that spool up DNA into chromosomes (SMC complexes) and enzymes
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evaluating specimens and requisitions, cell culture and harvesting, chromosome analysis, imaging and karyotyping, and reporting. In addition, the technologist will perform daily, weekly and monthly QC and
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Hirszfeld Institute of Immunology and Experimental Therapy Polish Academy of Sciences | Poland | 7 days ago
and growth, pathogenicity, and adaptation of bacteria to the environment. We are interested in processes such as, but not limited to, bacterial chromosome replication, signal transduction systems