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chromosome numbers (aneuploidy), but malignant cells sometimes exhibit chromosomal instability (CIN): the ongoing, cell-to-cell reshuffling of chromosomes that continuously generates new tumor variants
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the Job related to staff position within a Research Infrastructure? No Offer Description The project Most cancers carry abnormal chromosome numbers (aneuploidy), but malignant cells sometimes exhibit
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like functional metagenomics to investigate pathogen virulence and plasmid-chromosome associations. You will gain a unique interdisciplinary skillset: Molecular Biology: DNA extraction, host depletion
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that TEs fundamentally shape genome function and evolution by affecting gene expression, rewiring regulatory networks, and driving change in chromosome size and structure. In recent years, research
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that suppress recombination between incipient species are suggested to play a role to maintain species boundaries in sympatry. For example, chromosomal rearrangements may play a central role in local suppression
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at low levels within A. baumannii populations. You will use this to understand how chromosomal changes increase pathogenicity and provide an advantage in hospital settings. You will use a combination
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al, 2021; Orr. Mittmann et al, 2026 (Featured in the Press) which display increased distal recombination (end of the chromosomes), but the increase in the peri-centromeric region is still marginal. The
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Principles of Chromosomal Instability Cellular Senescence, Tumour Suppression and Organismal Ageing Topics covered during the second semester: Materials Sciences Laser Technology Cardiovascular Tissue
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myeloid leukemia (DSPII) Control of chromosome segregation during early development in mammals Development and characterization of a pig model for the study of Usher syndrome type 2C (USH2C) From Signal
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regulatory processes determining expression, activity and functional impact of key genes including FUT2. This will include CRISPRi to systematically silence DNA regions e.g. for FUT2 on chromosome 19