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the nematode C. elegans. Our lab integrates genetics, live imaging, quantitative analysis, and computational approaches to uncover the molecular mechanisms regulating aging and longevity. Minimum Qualification
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to our research project investigating brain dynamics and cellular molecular mechanisms in C. elegans that underlie transitions between sleep and wake states. You will conduct quantitative behavioral
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extensive experience in C. elegans genetics, molecular biology, and aging biology. Imaging using confocal microscopy. Certifications/Licenses Required Knowledge, Skills, and Abilities Experience in genetics
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, computational, and microscopic techniques to analyze behavioral and neuronal changes in C. elegans using a specialized microscopy, imaging platforms and computer vision analyses. Also assist with lab organization
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underpinnings of aging and the complete neuronal wiring diagrams of two sexes in the nematode C. elegans, the department has stood out through its diversity of thought, scientific questions and the experimental
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University of North Carolina at Charlotte | Charlotte, North Carolina | United States | about 2 months ago
will work in Dr. van Oosten-Hawle’s lab under the current NIH R01 grant. The student researcher is expected to maintain the lab’s C. elegans frozen database, maintain C. elegans growth, restock C
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the nematode C. elegans , with an emphasis on X-chromosome dosage compensation, which balances gene expression between XX hermaphrodites and XO males, and the specification of sexual fate. Previous work by
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, biochemical, and genetic approaches. To accomplish these aims, the incumbent will work with a range of model organisms and cultured cell systems, including C. elegans, D. melanogaster, HEK cells, and HeLa cells
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analysis C. elegans and mouse husbandry and experimentation Data analysis using a variety of software programs, and preparation of data for presentation Training of new lab members and functional supervision
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of the machine-learning assay in other worm phenotypes. Principal Duties and Responsibilities: 50% Strain maintenance & life history analysis Maintain C. elegans strains, perform genetic crosses and characterize