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mechanochemically-driven cell polarization evolves. You will focus on polarization of the C. elegans one-cell embryo, which is essential for establishment of one of the main body axes. This polarization event
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complete neuronal wiring diagrams of two sexes in the nematode C. elegans, the department has stood out through its diversity of thought, scientific questions and the experimental systems to answer them
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for the model nematodes C. elegans and C. remanei . Associated projects entail CRISPR/Cas9 genetic engineering, experimental evolution, genomics, and field sampling. The selected candidate will also mentor
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C. elegans and its natural parasites. Associated projects entail evolve-and-resequencing, quantitative trait mapping, and field sampling with spatial analyses. The selected candidate will also mentor
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Max Planck Institute for Heart and Lung Research | Bad Nauheim, Hessen | Germany | about 1 month ago
zebrafish, mouse, C. elegans, and more recently humans. This is a novel and quickly developing field of research where many open questions remain to be addressed including 1) the nature and trafficking
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, Caenorhabditis elegans, Mus musculus, and Homo sapiens, comparing short- and long-lived species. We will assess mRNA and protein expression across tissues and developmental stages, quantifying correlations between
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Responsibilities Prepare staged C. elegans samples and image by confocal microscopy Perform microinjections, genome editing and genetic crosses to generate new C. elegans strains Generate plasmid constructs by
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well as AGD, which are causing intolerable losses (c.20% annually). AGD is a primary driver of proliferative gill inflammation which impairs the respiratory capacity of fish leading to asphyxia, respiratory
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this field is the Integrated Stress Response (ISR), which output is orchestrated by the transcription factor ATF4. Current models, largely from C. elegans, suggest ATF4 activation is pro-longevity. However
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of Biology work on a wide range of cell systems and model organisms, including C. elegans, Drosophila, Tribolium, Xenopus, zebrafish, mice, yeast, maize, Ceratopteris, and others. The Department of Biology has