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Field
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secretion systems (T4SS) are bacterial nanomachines involved in the transfer of genetic material and intercellular communication. They play a major role in the dissemination of antibiotic resistance
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investigating how bacteria repair protein–DNA crosslinks induced by fluoroquinolone antibiotics. The project, co-supervised by Prof Stephan Uphoff, aims to understand the molecular mechanism of the bacterial
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free of adventitious agents (AAs) such as bacterial and fungal contaminants. Current AA detection methods require lengthy culture times and are not suitable for continuous manufacturing, where rapid
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to understand the molecular mechanism of the bacterial exonuclease VII (Exo7) repair complex, which removes adducts of stalled type II topoisomerases from DNA and contributes to antibiotic tolerance
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following areas: A strong background in microbiology, including experience with bacterial and/or fungal culture, antibiotic susceptibility testing, rapid molecular detection of resistance genes or pathogens
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candidate will investigate the functions of bile metabolites induced by bacterial infection. We aim to advance our understanding of how infection-stimulated bile metabolites influence intestinal defense
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. Experience with bacterial cultures and aseptic technique. Experience with molecular approaches to study bacterial survival and antibiotic resistance. Preferred Qualifications: ● Experience with bacterial
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to applicants with expertise in one or more of the following areas: A strong background in microbiology, including experience with bacterial and/or fungal culture, antibiotic susceptibility testing, rapid
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. Experience with bacterial cultures and aseptic technique. Experience with molecular approaches to study bacterial survival and antibiotic resistance. Preferred Qualifications: ● Experience with bacterial
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advanced measurement techniques to test these models in living cells. The detailed knowledge of bacterial physiology is combined with the sensitive measurement tools to develop innovative solutions