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, we found that GAA deficiency in PD resulted in engorged lysosomes which significantly disrupted AT1 and AT2 cellular architecture. Lysosomes are an essential component of autophagy which is important
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biology. This NIH-funded position is available to study the role of nuclear pore proteins in the regulation of chromatin architecture during neuronal differentiation. The successful candidate will have a
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chromatin architecture regulates fundamental DNA-templated processes including DNA replication, transcription, and DNA repair. Our research uses the budding yeast Saccharomyces cerevisiae as a model system to
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