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these centers, B lymphocytes undergo intense selection to produce high-affinity antibodies and long-lived memory B cells. While follicular helper T (Tfh) cells are critical to this process, recent discoveries by
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, and neonatal patients. Thus, practical experience is gained through daily exposure to red cell type and screen procedures, antibody identification and complex serologic evaluations; transfusion reaction
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University of North Carolina at Chapel Hill | Chapel Hill, North Carolina | United States | 2 months ago
/ML) and pharmacokinetic/pharmacodynamic (PK/PD) models that reduce reliance on animal testing and enable the quantitative evaluation of safety and efficacy for antibody and mRNA-LNP therapeutics
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mucosal antibody responses following vaccination. Thus, the project also has the potential to increase general knowledge about the use of nanoparticles in nucleic acid-based vaccines against mucosal
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antibody-based approach to intervene the malignancies 3) Identification of novel therapeutic target using high-throughput CRISPR genetic screen (e.g., metabolic pathway, mitochondria structure) in immune