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Research Group leader (UCO: 8725) Consultant: Silvie Trantirkova, Senior Researcher (UCO: 118502), Topic title: Protein in-cell NMR Spectroscopy in 3D Stem Cell-Derived Human Organ Models Annotation: In-cell
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Supervisor: prof. RNDr. Robert Vácha, PhD. Topic title: Designing Coiled-Coil Peptides for Controlled Membrane Fusion and Intracellular Delivery Annotation: Most approved drugs act on cell-surface targets
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Research 43(5):2575-89 (2015) Bösken CA, Farnung L, Hintermair C, Merzel Schachter M, Vogel-Bachmayr K, Blazek D, Anand K, Fisher RP, Eick D, Geyer M. The structure and substrate specificity of human Cdk12
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receptor (BCR) signaling and B-T cell interactions. Human genome contains large numbers of lncRNAs that can regulate various physiological cellular processes or contribute to the onset or aggressiveness
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testing targeted therapy options, e.g. using specific inhibitors of TFs or chromatin modification regulators that are currently available or in development. We have identified several TFs that might act as
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). We have identified candidate molecules that might act as novel regulators of the B cell migration or the balance between homing and survival in peripheral blood. This will be further investigated by