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Chemistry. The thesis project will focus on computational models for assessing exposure of organic pollutants in zebrafish. The position is for four years of doctoral studies, including participation in
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profiles and phospho status according to established protocols. The project builds directly on our previous work in zebrafish, where we established the telomerase-deficient premature aging model and showed
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Instituto de Investigação e Inovação em Saúde da Universidade do Porto (i3S) | Portugal | about 1 month ago
apply in vitro and in vivo methodologies in well-established animal models - mammalian cell lines, zebrafish and a mouse model of peripheral nervous system injury - to dissect the molecular mechanisms
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intellectual disability and zebrafish animal husbandry. The project is part of a larger effort in the lab to develop zebrafish models to screen therapeutic approaches. The TRA will be responsible
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that the pathogenic (ATTTC)58 triggers formation of abnormal nuclear (AUUUC)n aggregates. We have also confirmed (AUUUC)n toxicity by injection in zebrafish embryos, which caused developmental malformations and
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Chemistry. The thesis project will focus on computational models for assessing exposure of organic pollutants in zebrafish. The position is for four years of doctoral studies, including participation in
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-to-day operations of both a multiuser, Zebrafish and aquatic frog facility as well as working in other laboratory animal colonies Daily operation and upkeep of the facility including feeding
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regeneration. We accomplish these goals through the use of zebrafish as a model system and expand our studies into the fields of transcriptional regulation, cardiac mechanobiology, and stem cell biology. We
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additional assests will be prioritzed: Experience in sarcoma research or related cancer models Familiarity with epigenetic mechanisms and chromatin biology Experience with zebrafish models of cancer Strong
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. Responsibilities include maintaining zebrafish stocks, performing genotyping, generating new lines through microinjection, carrying out molecular biology tasks such as cloning, assisting postdocs and graduate