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). While mRNA vaccines have demonstrated rapid development and high efficacy, current formulations primarily protect against severe disease rather than preventing infection at mucosal entry points
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plasmid efficacy against WHO-priority AMR gene analogues in relevant bacterial hosts Bioprocess optimisation: Develop high-cell-density cultivation protocols in bioreactors, addressing plasmid stability
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PhD Studentship: Nanopore Technology for Rapid and Accurate Measurement of Antibiotic Concentrations
their use in field or point-of-care settings. This project aims to develop portable, nanopore-based sensors for the rapid and accurate quantification of antibiotic concentrations in environmental and clinical
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, more effective medical devices and reduce reliance on antibiotics, contributing to global AMR mitigation efforts. Training and Student Development: The student will gain interdisciplinary training in
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rather than the structured biofilms found in real-world environments. This project investigates how engineered surface topographies influence HGT dynamics, aiming to develop design principles for materials
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-pharmacological antifungal therapies. Approach and Methods: Develop and optimise laboratory models of fungal growth and resistance. Investigate how environmental stress factors (e.g. osmotic and nutrient stress