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biochemistry, genomics, molecular genetics, cell biology, and model organism systems to uncover the mechanisms by which histone mutations disrupt human development and lead to disease. Our ultimate goal is to
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genetic mutations. We aim to advance our understanding of these diseases and to develop and translate therapeutic strategies for future clinical practice. The applicant is expected to work on mouse models
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(including Crohn’s disease and ulcerative colitis) using molecular and cell biology, multi-omics technologies, murine models, and human tissues. We currently have three major focuses: 1) Innate lymphoid cells
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organoid culture, genetically engineered murine models, and human samples. The lab has successfully competed for various funding. The appointment is viewed as a training or transitional period preparatory to
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. Computational and bioinformatic skills. Experience in microscopy. Generation and analysis of mouse models. Handling of human samples. Molecular biology skills including CRISPR, cloning and qPCR. In vitro cell
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metrics since 2000. 2. Assess the Effects of 3-D Urban Structure on Extreme Humid Heat: Analyze variations in humid heat using Landsat thermal bands, MODIS, and humidity data, modeling how urbanization
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Position Summary The Ornitz Lab at WashU Medicine is seeking a highly motivated postdoctoral researcher with experience working with mouse models of development and disease. Candidates will have the
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combines human samples, mouse models, and in vitro culture system, and leverages single-cell technology, bioinformatic analysis, and mechanistic interrogations to revolutionize our understanding of gut
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their degree in the near future) in Cancer Biology or a related field. Proficiency in experimental techniques such as cell/organoid culture, library construction, imaging and handling animal models. Experience
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multidisciplinary approach, spanning basic biology and translational medicine using mouse models and patient samples, tackles complex questions with profound implications for human health. Projects are available