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translated eleven vaccine candidates, including viral vectors, recombinant proteins-in-adjuvants and a virus-like particle, into Phase 1 and 2 clinical trials in the UK and Africa. Over half of these trials
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viral (AAV) vectors. We propose to compare the capabilities of this instrument with that of commercially available mass spectrometry platforms and other methods. As part of this exciting and truly
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targeting. The project requires the culture and transduction of primary LRRK2 mutant and wild type astrocytes with lentiviral vectors to knockdown (shRNA) or enhance endogenous expression (CRISPR-a) of LRRK2
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