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The University of North Carolina at Chapel Hill | Chapel Hill, North Carolina | United States | 20 days ago
at Chapel Hill, for a self-motivated scientist to study the role of laminin-binding integrins in lung development, alveolar homeostasis, and alveolar repair. We utilize lung-specific transgenic mouse models
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. The winner will have to manage animal models, preferably transgenic Alzheimer's models such as the TgF344-AD; perform surgical procedures on laboratory animals, monitor animal welfare, and apply ethical
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duties of this position are the following: Transgenic mouse colony maintenance (breeding and genotyping). Mouse behavior analysis. Animal perfusion and brain tissue collection / brain sample processing
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drive projects forward to uncover novel biology. The job will require extensive cell culture of inducible pluripotent stem cells, development of transgenic mouse models, development of brain tumor models
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at the subcellular level and growing state, interaction with specific host cells using transgenic zebrafish lines, macrophage polarization). Test PA strains from various sources for persistence in zebrafish. Poster
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Accountabilities & responsibilities : The lab technician fellow will contribute to ongoing research projects exploring genetic interactions that influence lifespan, generate transgenic nematodes, perform lifespan
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to mechanical stimulation Methods and Approaches: The project combines state-of-the-art experimental and computational techniques, including: Transgenic mouse models and lineage tracing Orthodontic tooth movement
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for performing various animal husbandry duties in conventional, immunodeficient and transgenic/knockout rodent colonies. In addition, the Animal Technician will maintain animal rooms, monitor rodent colonies, and
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wild-type and transgenic mouse colonies, will set up matings and will work with mice on a routine basis. He/she/they will also carry out various laboratory procedures following established protocols
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with primary synovial cells obtained from joints from arthritis patients (e.g., CRISPR knock-outs and phosphoproteomics signaling), in vivo arthritis models in newly generated transgenic mice (e.g