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can be found on his website https://knightlab.ucsf.edu/ About the role: We are looking to hire a full-time lab manager who has experience working with rodents. A core responsibility of the position (~50
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related dementias. We use a combination of iPSC-based systems and transgenic mouse models coupled with novel approaches including single-cell sequencing, CRISPR–Cas9 screening, and interactome profiling
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-characterized human cohorts and preclinical transgenic mouse models, leveraging multi-omics and mechanistic approaches to generate high-impact, translational datasets. The successful candidate will work closely
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problems in the field of neurodegeneration. Among the key duties of this position are the following: Transgenic mouse colony maintenance (breeding and genotyping). Mouse behavior analysis. Animal perfusion
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perform a wide variety of procedures pertaining to characterization of different knock-out and transgenic models of cancer and metabolic diseases. Responsibilities Perform extensive mouse breeding Perform
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of normal and pathological physiology. It consists of a number of scientific and service departments and shared equipment for the research (http://www.fgu.cas.cz/en/ ). The Laboratory of Molecular Physiology
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Staff - Non Union Job Category Non Union Technicians and Research Assistants Job Profile Non Union Salaried - Laboratory Assistant Job Title Transgenic Unit - Laboratory Assistant Department
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. Research project activities may include: ⢠Mosquito breeding and behavioral experiments ⢠Generation of transgenic strains using CRISPR/Cas9 ⢠Molecular biology studies including DNA/RNA extraction, PCR
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translational projects employing single-cell sequencing, immune profiling, transgenic models, and molecular biology to uncover pathomechanisms and therapeutic targets in arthritis, osteoporosis, intervertebral
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, Mesp1, E-cadherin, N-cadherin). • Mechanical analysis of tissues in collaboration with biophysicists from the team 3. Development and optimization of protocols • Generation of transgenic lines