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neuroprotective effects. Camptothecin – A clinically relevant anticancer agent targeting Topoisomerase I. In collaboration with Prozomix Ltd. (an industrial leader in enzyme development), this project will
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global temperature target, this century, can only be achieved through global net negative emissions, where CDR removes more CO2 from the atmosphere than all human activity is emitting. Today, CDR removes
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the PhD student to propose targets to preserve liver metabolic health and prevent disease progression associated to poor dietary habits, which will be investigated in this project. This collaborative
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that underpin immune recognition by these proteins, and how they could be engineered to expand or otherwise improve their use in agriculture. Our target for developing new disease resistance is the most
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this challenge. Pathogens invade plant cells and hijack proteins that control protein synthesis, bending these processes to support pathogen growth. This project aims to target the protein-protein interactions
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interventions. These insights may ultimately lead to the identification of new targets for the development of therapies for ageing and age-related disease. For more information please contact: rebecca.c.taylor
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molecular switches that could be targeted by anti-fibrotic drugs. You will master • genome editing, • human iPSC culture and directed differentiation, • live cell biomechanical imaging, and • multiomics
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), computation (bioinformatics, machine learning, statistical analysis), working with animals (radio-tracking, animal handling/sampling), and deep knowledge of evolutionary biology and gerontology. The Norwich
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ecology and oceanography, the project will leverage large existing datasets on (i) the movement of migratory seabirds throughout their annual cycle, available via BirdLife’s Seabird Tracking Database (STD
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ability to evaluate fossil fuel CO2 (ffCO2) emissions is currently limited. ‘Bottom-up’ emissions estimates, based on inventory-style accounting and mobile tracking data, can differ significantly from each