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, therapy resistance, and disease progression. By pinpointing cell-type-specific vulnerabilities in the genome, we aim to identify novel therapeutic targets and inform personalized treatment strategies. Our
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. Your tasks will include the development, validation and application of suitable target and non-target LC/MS methods for characterizing the entry and degradation pathways of relevant organic
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EU MSCA doctoral (PhD) position in Materials Engineering with focus on computational optimization of
of strongest influence on the target properties. Moreover, the obtained data will be fed into a generative pre-trained transformer model (e. g. ChatGPT) to probe the potential of in-context learning for process
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, these models will be applied to clinical cohorts of individuals suffering from mental illness to perform patient stratification, discovery of new biological mechanisms and stratified drug target identification
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potential: targeted training and mentoring through the DKFZ International PhD Program and DKFZ Career Service Our Corporate Health Management Program offers a holistic approach to your well-being Contact
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internalization into tumor cells, ADCs release their cytotoxic payload, causing targeted cancer cell death via DNA or microtubule disruption. Beyond their direct cytotoxic effects, emerging evidence shows that ADCs
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, crystallization, or molecular aggregation/switching. The BEAM projects cover a wide spread of topics, including theoretical physics and chemistry work. For example, our targeted syntheses are supported by models
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targets for the development of novel natural product-based antibiotics. The research group Microbiome Dynamics invites talented and highly gifted candidates to apply as Doctoral Researcher (m/f/div) in
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imaging methodologies. In this project, novel techniques are being developed for tracking radio-labelled cells, either as cell populations or even individual cells. This is being achieved by combining whole
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. Importantly, neutrophils are involved in inflammatory diseases and cancer, making them an exciting new therapeutic target in the clinic. The applicant should have a master's degree in biology or biochemistry