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novel therapeutic targets and combination strategies to overcome microbiome-driven immune suppression in colorectal cancer. Key Responsibilities: Design and conduct experiments, data collection, and data
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PhD student (m/f/d) in the field of chemistry, chemical engineering, materials science or comparable
of the target materials based on the characterization results Using in silico pre-screening and synthesizability predictions to generate lead candidates for the synthetic exploration Reporting, documentation, and
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of the key targets identified by multiomics. A PhD or a Dr. rer. nat., Dr. biol. hum., or Dr. med. are possible. Remuneration is based on the Collective Agreement for the Public Sector of the Länder (TV-L
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, therapy resistance, and disease progression. By pinpointing cell-type-specific vulnerabilities in the genome, we aim to identify novel therapeutic targets and inform personalized treatment strategies. Our
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. Your tasks will include the development, validation and application of suitable target and non-target LC/MS methods for characterizing the entry and degradation pathways of relevant organic
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, these models will be applied to clinical cohorts of individuals suffering from mental illness to perform patient stratification, discovery of new biological mechanisms and stratified drug target identification
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. You have a strong academic track record and hold or are about to obtain an MSc or equivalent degree in a field related to our research. We value diversity and welcome applications from students of all
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EU MSCA doctoral (PhD) position in Materials Engineering with focus on computational optimization of
of strongest influence on the target properties. Moreover, the obtained data will be fed into a generative pre-trained transformer model (e. g. ChatGPT) to probe the potential of in-context learning for process
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internalization into tumor cells, ADCs release their cytotoxic payload, causing targeted cancer cell death via DNA or microtubule disruption. Beyond their direct cytotoxic effects, emerging evidence shows that ADCs
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potential: targeted training and mentoring through the DKFZ International PhD Program and DKFZ Career Service Our Corporate Health Management Program offers a holistic approach to your well-being Contact