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inhibitors and bifunctional molecules Experience in using structural guidance for ligand design Experience in cell viability and lysis assays, fluorescent reporter assays, flow cytometry, CETSA, ELISA, Western
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approaches including live-cell fluorescence microscopy, cryo-super resolution structured illumination microscopy (SIM), and cryo-electron/X-ray tomography. You will lead research into antimicrobial responses
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Prevention Initiative (COPI). The successful applicant will develop the simulation model capabilities using the PRIMEtime structure to estimate the impacts of the suite of interventions being implemented in
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for carrying out research to develop iPSC-derived lung cell models. Working within a team of biochemists, cell and structural biologists, you will perform experimental work to apply omics technologies, advanced
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cytometry, genomics, and molecular biology. We maintain close collaborations with immunologists, structural biologists, and clinicians. Essential Qualifications and Skills We are seeking a creative
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research projects require a creative, multidisciplinary approach, and as such provide opportunities across parasitology, structural biology, biochemistry and cell biology including single molecule
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approaches, as well as being able to build on expertise in bacteriology, cell biology, structural biology and biochemistry in the group. You should hold, or be close to completion of, a PhD/DPhil in biological
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including protein purification, SDS-PAGE, and western blotting. The post holder should be familiar with bioinformatics tools and databases (BLAST, protein structure prediction tools) and have basic
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: 1089, bioRxiv (2025)) by carrying out protein biochemical, cell biological, and live cell fluorescence imaging experiments. Associated structural analysis of the proteins by cryo-electron microscopy will
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structural), ECG, and genetics, to model disease trajectories and improve risk prediction in cardiomyopathies. The successful applicant will work closely with the PI to deliver research projects, supervise