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Your position The project aims to develop novel anti-biofilm compounds that can be used to treat biofilm-related infections caused by a range of bacterial pathogens. Based on structural data
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. This position offers an exciting opportunity to contribute to cutting-edge research in structure-based discovery of anti-biofilm compounds. Our research group at the Biozentrum is embedded in the National Centre
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spectrometry-based proteomics and structural biology, and applies these technologies to study amongst others cancer, auto-immune disorders, immunology, infections, and infectious diseases. Additionally
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structure-based methods to identify novel small-molecule therapeutics. Tackling this challenge is critical for enabling more precise and efficient discovery efforts against complex biological targets
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) the creation of new-based DNA nanostructures as a molecular template to hold proteins to facilitate molecular imaging by single-particle Cryo-Electron Microscopy (Cryo-EM); and (2) the development of DNA-based
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; length of the term will be discussed during the interview process. Continuation past the term length discussed will be based on university need, performance, and/or availability of funding. POSITION
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constraints into ML frameworks, and creatingLLM-based agentsto assist with mechanistic model construction and knowledge curation. Track B (Mechanistic modeling):Building and analyzingmultiscale modelsthat
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-informed neural networks (PINNs) for integrating mechanistic constraints into ML frameworks, and creating LLM-based agents to assist with mechanistic model construction and knowledge curation. Track B
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comprehensive benefits package to eligible employees, based on position, which includes: Medical, prescription drug, and dental coverage Paid vacation, holidays, and various leave programs Competitive retirement
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spectrometry-based metabolomics data, in part based on generative AI models of chemical structures. The position is available starting July 2025, and will remain open until excellent fits are found.The