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pluripotent stem cells for the study and treatment of diabetes. We have a wide diversity of projects involving stem cells differentiation, genetic engineering with CRISPR, disease modeling, transplantation
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the Broad Institute of Harvard and MIT. Current areas of focus in the lab include: Leukemia biology (pathogenesis, hematopoiesis, and stem cell biology) Dendritic cell development, function, and malignant
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focusing on myocardial biology and heart failure pathophysiology. Job functions will involve cell culture techniques including work with induced pluripotent stem cells (iPSCs) and iPSC-derived
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dynamic interactions with therapeutic immune cells. While expertise in in vitro immunotherapy modeling is highly desirable, candidates with the following experience will also be considered: stem cell
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, optogenetics, genome engineering, induced pluripotent stem cell differentiation to neurons/organoids, and in vitro and in vivo electrophysiological measurements. Our long-term scientific goal is to dissect
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Parkinson’s disease, integrating human stem cell–derived neuronal models, in vivo studies and translational human tissue analysis. The work focuses on how oxidative stress, mitochondrial dysfunction and
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will be determined by the supervisor. What you'll do Cell culture and maintenance of pluripotent stem cells and differentiating inner ear and skin organoids under sterile conditions Immunohistochemistry
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or induced pluripotent stem cells (iPSCs) derived from patient peripheral blood mononuclear cells. Validation will include stimulating or inhibiting target pathways using antagonists or agonists, or using gene
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. Our biomedical research laboratory uses human pluripotent stem cells for the study and treatment of diabetes. We have a wide diversity of projects involving stem cells differentiation, genetic
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). About the team You will join the lab of Dr Sophie Kellaway as part of the Blood Cancer and Stem Cell group (https://bcasc.co.uk/ ). You will work closely with a research fellow on the same project. You