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ERC-funded pioneering research line at the interface of neuroimmunology, stem cell biology, and neurodegeneration. Contribute to the setup and optimization of novel xenotransplantation models
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engineering, environmental engineering, and mechanical engineering. School of Life Sciences: structural biology and biophysics, cell biology, stem cell research and therapy, neural and behavioral biology
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on modified mesenchymal stem cells and immunoeffector cells, through gene transfer and/or programmed glycosyltransferase stereosubstitution, to increase the localization of these cells in target tissues, as
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to protect MN axons against degeneration in ALS. To achieve this objective, our team uses induced pluripotent stem cell (iPSC)-derived MNs to investigate RNP granule dynamics in a physiological model. We
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-1209; Nature, 2019, Mar; 567(7746):113-117; Cell Stem Cell, 2018, Oct 4; 23(4):557; NatureCommunications, 2017 Nov 15;8(1):1523; TheEMBO Journal, 2016 Jan 4;35(1):24-45; J Cell Science, 2015 Dec 1;128(23
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George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Târgu Mureș | Romania | 21 days ago
/pharmaceutics15112637. Advanced Progress in the Role of Adipose-Derived Mesenchymal Stromal/Stem Cells in the Application of Central Nervous System Disorders, Haiyue Wu et al Int J Mol Sci, 2024. doi: 10.3390
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inevitable natural process that impacts quality of life and increase the risk of cardiovascular diseases. In the Rocha lab we use animal and human induced pluripotent stem cell (hiPSC)-derived cardiovascular
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genomics, transcriptomics, and epigenomics with mechanistic studies using in vitro and in vivo models to dissect B-ALL and related hematologic malignancies. The lab also studies normal hematopoietic stem
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candidate will build a comprehensive 3‑D agent‑based Cytosim model of neural‑stem‑cell (NSC) mitotic spindle positioning, incorporating all mechanisms identified and suggested by experiments. It will involve
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stem cell (hiPSC) culture techniques; 2) cell culture in 3D strategies and bioreactor technology; 3) culture of kidney organoids and 4) analytics for characterization of cells and organoids (RT-PCR,flow