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PhD Studentship: Preclinical modelling and therapeutic targeting of glioblastoma infiltrative margin
infiltrative margin will be re-programmed to generate induced pluripotent stem cells as a patient-matched toxicity control. Research Environment: Applications are invited for a 4-year fully-funded PhD
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their anticancer and neuroprotective activities in human cell-based assays. Generate SAR data linking specific enzymatic modifications to pharmacological properties. This PhD project offers extensive research
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:10.1038/s41551-022-00951-w Investigating the role of autophagy and mitochondrial function in leukaemic stem cells Supervisors: Vignir Helgason , Eric Kalkman Our lab is interested in biological processes
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. To address these questions, the student will use isogenic SARM1 knock-in human induced pluripotent stem cells (iPSCs) with GoF mutations (E340K, del275-276 and A275V), SARM1 knockout and a homozygous intronic
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BBSRC Yorkshire Bioscience DLA Programme: Human Stem Cell-Based Approaches for Neurotoxicity Testing of Environmental Contaminants (CASE Project) School of Biosciences PhD Research Project
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: Refinement of Stem Cell-Based Strategies for Ischemic Lesion Recovery” (reference: RESCUE #1), funded by the Portuguese Foundation for Science and Technology (FCT) under Call MPr-2023-12, taking place at RISE
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, research is vital to advance diagnosis, treatment and prevention. Our strength is in identifying and designing novel therapeutic strategies that will lead to clinical trials. PhD: 3-4 years full-time; 5
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BBSRC Yorkshire Bioscience DLA Programme: Directing Stem Cell Fate – The Role of Ribosomal RNA Modifications School of Biosciences PhD Research Project Competition Funded Students Worldwide Dr E
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BBSRC Yorkshire Bioscience DLA Programme: Genomics and development of an exaggerated sexual trait in stalk-eyed flies School of Biosciences PhD Research Project Competition Funded Students
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, including single-cell genomics (Wright, Lloyd), sexual selection and reproduction (Wright, Pomiankowski, Hemmings, Wigby), gene editing (Dasmahapatra), experimental approaches (Wigby), and stalk-eyed fly