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Collaborating across teams Selection criteria: PhD/DPhil in neuroscience or cell/molecular biology Expertise in stem cell culture, neuronal differentiation and cellular assays Knowledge of neurodegenerative
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Hematopoietic stem and progenitor cells (HSPCs) are responsible for lifelong maintenance of the blood system, yet their function progressively declines with age. Chronic inflammation, a hallmark of aging
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seek to understand the genetic and epigenetic basis of organ regeneration and tumorigenesis. We study the properties of stem/progenitor cells in diverse epithelial tissues (with a primary focus on lung
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000 individuals in UK. As part of a wider strategy to develop a deep human experimental medicines platform, this project aims to mainly focus on using novel human in vitro platforms using IBD gut stem
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induced pluripotent stem cells (iPSCs); differentiation of pluripotent cells into neuronal lineages; genome engineering using CRISPR/Cas9; molecular biology and biochemistry laboratory techniques (e.g
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, research is vital to advance diagnosis, treatment and prevention. Our strength is in identifying and designing novel therapeutic strategies that will lead to clinical trials. PhD: 3-4 years full-time; 5
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-edge research across diverse disciplines such as stem cell biology, aging and neurodegeneration, sleep, neurodevelopment, psychotic disorders, and precision health. Our department is also collaborating
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also have conceptual, empirical, or ethical consequences. Given the ubiquitous role of lineages in biology (central to development, regeneration, stem cell biology, cancer biology, and more), a clearer
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: Refinement of Stem Cell-Based Strategies for Ischemic Lesion Recovery” (reference: RESCUE #1), funded by the Portuguese Foundation for Science and Technology (FCT) under Call MPr-2023-12, taking place at RISE