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Leukemia DC15: Novel preclinically-validated GATA3 inhibitor/degrader as a therapy for T-cell Acute Lymphoblastic Leukemia DC16: Targeting Metabolic Pathways in Leukemic Stem Cells for AML Treatment
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stem cells (satellite cells) can be guided by anatomical and environmental signals to generate muscle fibers that are more resistant to disease. Using a unique collection of genetically engineered
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of scientific publications in relevant fields. Experience with models of myopathies or inflammation. Familiarity with stem cell-derived muscle models or 3D culture systems (including physiological
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Supervisor: prof. RNDr. Robert Vácha, PhD. Topic title: Designing Coiled-Coil Peptides for Controlled Membrane Fusion and Intracellular Delivery Annotation: Most approved drugs act on cell-surface targets
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Supervisor: prof. RNDr. Robert Vácha, PhD. Topic title: Overcoming the Endosomal Barrier: Design Principles of Fusogenic Proteins for Lipid Vesicles Annotation: Cancer remains one of the leading causes
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- and stem cell biology, and great synergy with renowned research groups. More information on the IMMENS and open positions available at the Åbo Akademi University in Turku can be found here: https
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initiation and progression. This work has recently expanded to include investigations into how metabolism and autophagy influence the biology of embryonic and cancer stem cells. For more information about our
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health. We are home to five Nobel laureates who have advanced the understanding of cancer, neurodegenerative diseases, aging and stem cells. Pride Values UCSF is a diverse community made of people with
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to identify candidate disease-causing variants. You will develop model systems, e.g. genome-editing of immune or induced pluripotent stem cells (iPSC) with specific patient-derived genetic variants. We aim
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an active role in shaping future research directions. Applicants should hold (or be close to completing) a PhD in molecular biology, stem cell biology, genetics or a related discipline, with strong technical