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Field
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of an iPSC model of mutations observed in patients - Characterization of defects at the cellular level - Characterization of defects at the transcriptomic level The successful candidate will work in the “mRNP
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/Qualifications • PhD in microbiology, molecular biology, or related field • Strong experience in bacteriology and molecular mechanisms of pathogenesis • Previous experience with insect models and host
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-analysis and modelling are particularly encouraged to apply. Where to apply E-mail marcello.solinas@univ-poitiers.fr Requirements Research FieldNeurosciencesEducation LevelPhD or equivalent Research
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on the role of epigenetic dysregulation for future clinical applications, particularly on their common Mantle cell lymphoma (MCL) model, through their French networks (LYSA, Carnot Institute CALYM) and European
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modeling), and stem cell biology (reprogramming and differentiation) are paving the way to new concepts that will undoubtedly improve skeletal regenerative strategies. Our strong and recognized expertise
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, advanced co-culture organoid assays, and in vivo models to decode the mechanisms underlying CAF-driven CRC evolution. Access to single cell RNA sequencing and spatial transcriptomics data from active
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and process behavioral and electrophysiological data • Model behavior based on diffusion models and make explicit link with neurophysiological data • Conduct detailled statistical analysis • Write
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of these ESIPT/TADF assemblies and of some model reference compounds. Most calculations will be conducted using DFT and TDA-DFT methods via the ORCA 5.0 software, which allows for evaluating spin-orbit coupling
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dozen input variables). The foreseen approach would be to build on recent developments in using CNNs for Species Distribution Models (e.g. Deneu et al 2021, Morand et al 2024) to summarise the complex
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, we propose to investigate a new approach that combines the benefits of a molecular alphabet extension with those of modifying the topology of the DNA sugar-phosphate backbone. Our model will be based