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collaboration activities. This includes the Chair of Spatial Information and Modelling, which is at the same time leading the IOER Research Area under the same title. Both TUD and IOER are globally oriented
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integrating single-nucleus epigenomic profiling of brain immune cells with high-resolution spatial transcriptomics. The PhD candidate will characterize epigenetic and transcriptional states of immune cells in
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Work Location(s) Number of offers available1Company/InstituteCentre of Studies in Geography and Spatial PlanningCountryPortugalState/ProvinceCoimbraCityCoimbraGeofield Contact City Coimbra Website https
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Generative AI Integration Generative procedural urban modeling and rule induction Semantic enrichment and automated feature extraction Reconstruction or inference of structural detail from sparse spatial
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transfer; spatial neighborhood/domain analysis; multi‑omic modeling for RNA+protein where applicable. Pipeline automation & reproducibility – 10% Implement/maintain Snakemake/Nextflow workflows with
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; environmental exposures and resilience to heat, flooding, and pollution in cities; geography of emerging diseases; health co-benefits from urban sustainability transitions; GIS, spatial modeling, and data-driven
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and human activities. CESBIO scientists make extensive use of remote sensing technologies to monitor environmental changes across spatial and temporal scales and to develop models that address key
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vulnerability Single-cell and spatial transcriptomic analysis of treated organoids and tumour Computational modelling of cell state rewiring network Functional validation of identified targets in various tumour
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fibroblast identity and function within liver tumours and how these cells shape anti-tumour immune responses. The student will use in vivo cancer models, spatial tissue analysis and immunological profiling
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-term epigenetic reprogramming in microglial cells, and microglia–T cell interactions. Using state-of-the-art approaches including single-cell and spatial transcriptomics, functional imaging, and