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Deutsches Zentrum für Neurodegenerative Erkrankungen | Ulm, Baden W rttemberg | Germany | about 2 months ago
sclerosis (ALS) and Parkinson’s disease. Using next-generation sequencing, we have identified Mendelian disease genes that cause autosomal-dominantly inherited ALS. We have developed innovative disease models
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. The research in the PhD project will focus on core spatio-temporal machine learning method development, including: generative models for grid-based and particle-based spatio-temporal data; controlled generation
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the tissue response around the materials will be followed by multimodal approaches including (among others) time-lapsed in vivo imaging, multiphoton intravital microscopy, spatial transcriptomics and
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scRNASeq and spatial transcriptomics datasets, including probing gene signature expression and comparing expression between groups using correct statistical models (e.g., Linear Mixed Model, Bayesian
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of priority elasmobranch species in the study area, while managing and analysing large telemetry datasets, and integrating environmental/spatial data to address key research questions on species ecology and
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applied questions such as environmental management and risk assessment. For more information on EnvStat, please see https://www.helsinki.fi/en/researchgroups/environmental-and-ecological-statistics TWO
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neurodevelopmental and neuropsychiatric disorders using mouse as a model organism. The primary function of this position includes functional characterization of genetically modified mice carrying disease-related
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crosstalk with tumor cells, immune cells and the vasculature. We perform mostly in vivo studies, combining lineage tracing and depletion models, flow cytometry, confocal microscopy and unbiased approaches
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-temporal machine learning method development, including: generative models for grid-based and particle-based spatio-temporal data; controlled generation methods for data assimilation; and graph-based multi
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demonstrates relevant skills, such as 3-dimensional and spatial design capability and a creative, problem-solving approach. Proficient with computer-aided drafting and 3D modeling software. (The Harvard Art