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molecular biology researcher with expertise in biomedical research and in the operation and support of state-of-the-art single-cell and spatial transcriptomics and metabolomics instrumentation and assays
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. Volkers M, Loughrey CM, Macquaide N, Remppis A, DeGeorge BR, Jr., Wegner FV, Friedrich O, Fink RH, Koch WJ, Smith GL, and Most P (2007) S100A1 decreases calcium spark frequency and alters their spatial
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an integrative approach that combines advanced multiomics, spatial transcriptomics, and structural biology with physiological assessments. By selectively perturbing key gene expression programs during homeostasis
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., Wegner FV, Friedrich O, Fink RH, Koch WJ, Smith GL, and Most P (2007) S100A1 decreases calcium spark frequency and alters their spatial characteristics in permeabilized adult ventricular cardiomyocytes
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immunology through innovative spatial analysis of the tumor microenvironment. Requirements Successful candidates will have a PhD, MD, or equivalent degree in immunology, cancer biology, pathology, or a related
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clinical prediction of progression remains difficult, leading to over- and undertreatment of women with particularly early breast cancer. Over the past decade, spatial tissue analysis techniques have been
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mechanisms involving genetic, epigenetic and chromatin organisation factors governing the cell-type specific response to ARS mutations. Therefore, integrative genome-wide cis-regulatory network analysis
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or local scales due to spatial, temporal, and sectoral heterogeneities. Moreover, the availability and quality of energy-related models and datasets at these levels are often limited, further complicating
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monitoring Statistical analysis and modelling of relevant data (e.g. environmental data). Publishing results in peer-reviewed scientific journals. Fisheries management and conservation (e.g. biodiversity
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. At the Copernicus Institute, the Amazon rainforest and its spatially cascading transitions have been studied for years using custom made data analysis and modelling methods. Within the NWO-Summit project EMBRACER