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prostate cancer; 2) Deciphering the epigenetic mechanisms of oncogenic gene upregulation driven by non-canonical promoters; 3) Discovery of novel druggable regulators of neuroendocrine surface protein target
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human cancer based on their cancer driver gene mutations. A new project in the lab is aimed at understanding the mechanism of natural killer mediated anti-tumor effects in LKB1-mutant lung adenocarcinoma
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, including super-resolution microscopy, and correlative light-cryo-electron microscopy (cryo-CLEM), to elucidate key steps of viral life cycle and the mechanism of virus restriction by host factors. Highly
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