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of the project is to elucidate molecular intra- and extracellular mechanisms of signaling modulating myeloid cells' immune responses. The project is supported by Innosuisse and has a translational goal aiming to
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, muscular dystrophies, neurodegenerative diseases, and cancer. Despite its importance, the molecular mechanisms by which PGC-1α-a large, predominantly disordered protein with only a single structured RRM
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This project is flanked by basic reasearch projects i) developing novel chemical probes and degraders to dissect mechanisms of adverse effects in cancer and metabolism. For a summary see: https://p3.snf.ch
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the Department of Biomedicine at Mattenstrasse 28, 4057 Basel. Project: The aim of the project is to elucidate molecular intra- and extracellular mechanisms of signaling modulating myeloid cells’ immune
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of the project is to understand the role of the second messenger c-di-GMP in E. coli bacteriophage infection and propagation and to investigate mechanisms that allow the host to escape phage killing by modulating