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Field
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nanomedicines. In this project specifically, we aim to better understand the interactions between nanomedicines and the cell (membrane). Building upon previous work in the host group, the PhD candidate will use
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fuel cells. Today’s fuel cells rely heavily on fluorinated polymers—such as Nafion ionomers for proton conductivity or PTFE coatings for water management. However, per- and polyfluoroalkyl substances
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for regulating mammalian cells using engineered proteins, as well as RNA and other combinations, for the treatment of cancer, such as CAR T cells, autoimmune and rare diseases. In our group, we use and develop
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3 Year, full-time funded PhD Studentship Eligibility: Home UK/EU and International applicants Bursary p.a.: Bursary equivalent to UKRI national minimum stipend plus fees (current 2025/26 bursary
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. However, isothiocyanates have been shown to possess hormetic effects (stimulation at low doses and inhibition at high doses) on cell growth. We have shown that high doses of isothiocyanates have anti-cancer
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chemistry, cell and molecular biology, biochemistry Honors (first class) or MSc degree in Chemistry/Pharmacology/Pharmaceutical Sciences Essential experience: Synthetic/medicinal chemistry (small molecule
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following criteria: BSc, including synthetic chemistry, cell and molecular biology, biochemistry Honors (first class) or MSc degree in Chemistry/Pharmacology/Pharmaceutical Sciences Essential experience
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transcriptomics and single-cell RNA sequencing on patient samples • Mining and analyzing public cancer databases (TCGA, GEO, etc.) and omics data • Inferring TLS formation and maturation stages from
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with UV and radioactive detector, dose calibrator, automatic gamma counter, digital autoradiography, animal blood cell counter, and a range of small animal imaging systems (bioluminescence/fluorescence
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of cell division driven by CDV proteins Job requirements We aim to reconstitute the intriguing archaeal cell division (CDV) proteins in liposomes to form a filamentous ring that contracts and hence deforms