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Applications are invited for a fully funded 4-year PhD studentship based in the Department of Biochemistry, University of Cambridge, and the new AstraZeneca Discovery Centre in Cambridge
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to tumour growth, metastasis formation, therapy response and immunosuppression. This research project will investigate the interplay between different CAF populations and malignant cells in pancreatic primary
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chromatin profiling methods along with CRISPR/Cas9-meduated cell line engineering and various animal models. You will study the effects of the activation or depletion of chromatin-modifying enzymes using
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processes associated with CIN [1], leveraging single-cell DNA sequencing understand CIN heterogeneity [2], and development and implementation of machine learning and AI models to imaging data [3]. The student
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their website at https://www.carroll-lab.org.uk/ Prostate cancer is the most common cancer in men in the UK and every year thousands of men die from this disease. Prostate cancer was thought to be one type
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We are looking for a full-time Research Assistant in Dr Fengzhu Xiong's lab at the Gurdon Institute, University of Cambridge. The successful candidate will be involved in studies of collective cell
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stability and how these impact cell state changes. Recently, we have demonstrated the profound impact of G-quadruplexes on the transcription of cancer-related genes and in super-enhancer function. At the core