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within different compartments of a single cell in live animals, enabling us to examine hypotheses in a truly physiological context. In this project, you will contribute to both engineering and neurobiology
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of Chemistry is looking for a PhD-candidate to study autoantigen-specific cell therapies employing synthetic chimeric autoantigen-receptors (sCAARs): PhD position in Translational Chemical Immunology Antigen
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take these variations into account. A vital feature shared by all these diverse blood vessels is the presence of endothelial cells (ECs), the specialized cells that line the vessel lumens and are in
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for proper cell function. However, transcription by RNA polymerases can be blocked by DNA damage on the DNA template, for example by UV-light or other chemicals. Transcription-blocking DNA damage can therefore
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Your job Plastic pollution in the environment is a global issue that warrants in-depth investigation of potential health hazards towards infants. Are you passionate to work with stem cell-based
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the information stored in our genome. Especially in germ cells and early embryos, where transcription is absent, regulation of translation is crucial for controlling protein levels and guiding development. In
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The Department of Chemical Biology and Immunology (CBI) of the Leiden Institute of Chemistry is looking for a PhD-candidate to study autoantigen-specific cell therapies employing synthetic chimeric
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bacteria and eukaryotes, relatively little is known about the cell biology and ecological roles of archaea. A prominent feature of archaea is the extraordinary diversity of their viruses. Archaeal viral
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of mRNAs by ribosomes is a key step in decoding the information stored in our genome. Especially in germ cells and early embryos, where transcription is absent, regulation of translation is crucial
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underlying inherited forms of SCD, with the aim of developing new therapeutic strategies. In this context, the role of cell types other than cardiomyocytes is becoming increasingly relevant, opening up